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Zifex 100/200

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ZIFEX-100

ZIFEX-200

 

(Cefixime Tablets USP)

COMPOSITON

ZIFEX-100

Each film-coated tablet contains:

Cefixime USP and Trihydrate

equivalent to Anhydrous Cefixime           100 mg.

 

ZIFEX-200

Each film-coated tablet contains:

Cefixime USP and Trihydrate

equivalent to Anhydrous Cefixime           200 mg.

 

Description

Cefixime is an orally active cephalosporin antibiotic which has in-vitro bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms .

 

INDICATIONS

  1. Upper Respiratory Tract Infections; e.g., bacterial pharyngitis, tonsillitis, otitis media,sinusitis.
  2. Lower Respiratory Tract Infections ;e.g., bronchitis.
  3. Urinary Tract Infections; e.g., acute cystitis.
  4. Uncomplicated gonorrhoea.

 

DOSAGE AND DIRECTIONS FOR USE

Adults and Children over 12 Years:

The recommended adult dosage is 200-400mg daily given either as a single dose or in divided doses.

 

CONTRA-INDICATIONS

Allergy to cephalosporins.Cefixime is contra-indicated in patients with renal impariment with a creatinine clearance below 60ml/min.

 

Drug Interaction

No significant interactions have been reported to date

 

Adverse Effects

Gastrointestinal Disturbances: The most frequent side effects seen with Cefixime are diarrhoea and stool changes.

Moderate to severe diarrhoea has been reported. Other gastrointestinal side effects seen less frequently are nausea, abdominal pain dyspepsia, vomiting and flatulence. Pseudomembranous colitis has been reported.

 


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