Zifex 100/200
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ZIFEX-100
ZIFEX-200
(Cefixime Tablets USP)
COMPOSITON
ZIFEX-100
Each film-coated tablet contains:
Cefixime USP and Trihydrate
equivalent to Anhydrous Cefixime 100 mg.
ZIFEX-200
Each film-coated tablet contains:
Cefixime USP and Trihydrate
equivalent to Anhydrous Cefixime 200 mg.
Description
Cefixime is an orally active cephalosporin antibiotic which has in-vitro bactericidal activity against a wide variety of Gram-positive and Gram-negative organisms .
INDICATIONS
- Upper Respiratory Tract Infections; e.g., bacterial pharyngitis, tonsillitis, otitis media,sinusitis.
- Lower Respiratory Tract Infections ;e.g., bronchitis.
- Urinary Tract Infections; e.g., acute cystitis.
- Uncomplicated gonorrhoea.
DOSAGE AND DIRECTIONS FOR USE
Adults and Children over 12 Years:
The recommended adult dosage is 200-400mg daily given either as a single dose or in divided doses.
CONTRA-INDICATIONS
Allergy to cephalosporins.Cefixime is contra-indicated in patients with renal impariment with a creatinine clearance below 60ml/min.
Drug Interaction
No significant interactions have been reported to date
Adverse Effects
Gastrointestinal Disturbances: The most frequent side effects seen with Cefixime are diarrhoea and stool changes.